Research

Publicaties 2019

Smulders MW, Kietselaer BLJH, Wildberger JE, Dagnelie PC, Brunner-La Rocca HP, Mingels AMA, van Cauteren YJM, Theunissen RALJ, Post MJ, Schalla S, van Kuijk SMJ, Das M, Kim RJ, Crijns HJGM, Bekkers SCAM. Initial Imaging-Guided Strategy Versus Routine Care in Patients With Non-ST-Segment Elevation Myocardial Infarction. J Am Coll Cardiol. 2019 Nov 19;74(20):2466-2477.

Lee KK, Ferry AV, Anand A, Strachan FE, Chapman AR, Kimenai DM, Meex SJR, Berry C, Findlay I, Reid A, Cruickshank A, Gray A, Collinson PO, Apple FS, McAllister DA, Maguire D, Fox KAA, Newby DE, Tuck C, Keerie C, Weir CJ, Shah ASV, Mills NL. Sex-Specific Thresholds of High-Sensitivity Troponin in Patients With Suspected Acute Coronary Syndrome. High-STEACS Investigators. J Am Coll Cardiol. 2019 Oct 22;74(16):2032-2043.

Downes K, Megy K, Duarte D, Vries M, Gebhart J, Hofer S, Shamardina O, Deevi SVV, Stephens J, Mapeta R, Tuna S, Al Hasso N, Besser MW, Cooper N, Daugherty L, Gleadall N, Greene D, Haimel M, Martin H, Papadia S, Revel-Vilk S, Sivapalaratnam S, Symington E, Thomas W, Thys C, Tolios A, Penkett CJ, Ouwehand WH, Abbs S, Laffan MA, Turro E, Simeoni I, Mumford AD, Henskens YMC, Pabinger I, Gomez K, Freson K. Diagnostic high-throughput sequencing of 2396 patients with bleeding, thrombotic and platelet disorders. Blood. 2019; 134 (23): 2082-2091. 

Damoiseaux J, Andrade LEC, Carballo OG, Conrad K, Francescantonio PLC, Fritzler MJ, Garcia de la Torre I, Herold M, Klotz W, Cruvinel WM, Mimori T, von Muhlen C, Satoh M, Chan EK. Clinical relevance of HEp-2 indirect immunofluorescent patterns: the International Consensus on ANA patterns (ICAP) perspective. Ann Rheum Dis. 2019 Jul;78(7):879-889.

Gorman K, Meyer E, Grozeva D, Spinelli E, McTague A, Sanchis-Juan A, Carss K, Bryant E, Reich A, Amy L Schneider A et al. Henskens Y (collaborator). Bi-allelic loss-of-function CACNA1B mutations in progressive epilepsy-dyskinesia. Am J Hum Genet. 2019; 104 (5): 948-956.

Damoiseaux J, Vulsteke JB, Tseng CW, Platteel ACM, Piette Y, Shovman O, Bonroy C, Hamann D, De Langhe E, Musset L, Chen YH, Shoenfeld Y, Allenbach Y, Bossuyt X. Autoantibodies in idiopathic inflammatory myopathies: Clinical associations and laboratory evaluation by mono- and multispecific immunoassays. Autoimmun Rev. 2019 Mar;18(3):293-305.

Boswijk E, Sanders KJC, Broeders EPM, de Ligt M, Vijgen GHEJ, Havekes B, Mingels AMA, Wierts R, van Marken Lichtenbelt WD, Schrauwen P, Mottaghy FM, Wildberger JE, Bucerius J. TSH suppression aggravates arterial inflammation - an 18F-FDG PET study in thyroid carcinoma patients. Eur J Nucl Med Mol Imaging. 2019 Jul;46(7):1428-1438.

Vroemen WHM, van Doorn WPTM, Kimenai DM, Wodzig WKWH, de Boer D, Bekers O, Meex SJR. Biotin interference in high-sensitivity cardiac troponin T testing: a real-world evaluation in acute cardiac care. Cardiovasc Res. 2019 Dec 1;115(14):1950-1951.

Fuchs CJ, Hermans WJH, Holwerda AM, Smeets JSJ, Senden JM, van Kranenburg J, Gijsen AP, Wodzig WKHW, Schierbeek H, Verdijk LB, van Loon LJC. Branched-chain amino acid and branched-chain ketoacid ingestion increases muscle protein synthesis rates in vivo in older adults: a double-blind, randomized trial. Am J Clin Nutr. 2019; 110 (4): 862-872. 

Simons N, Debray FG, Schaper NC, Kooi ME, Feskens EJM, Hollak CEM, Lindeboom L, Koek GH, Bons JAP, Lefeber DJ, Hodson L, Schalkwijk CG, Stehouwer CDA, Cassiman D, Brouwers MCGJ. Patients with aldolase B deficiency are characterized by an increased intrahepatic triglyceride content. J Clin Endocrinol Metab. 2019 104, 11, p. 5053-5061 9 p. 

Telgenkamp I, Kusters YHAM, Schalkwijk CG, Houben AJHM, Kooi ME, Lindeboom L, Bons JAP, Schaper NC, Joris PJ, Plat J, Mensink RP, Stehouwer CDA, Brouwers MCGJ. Contribution of Liver Fat to Weight Loss-Induced Changes in Serum Hepatokines: A Randomized Controlled Trial. J Clin Endocrinol Metab. 2019 Jul 1;104(7):2719-2727.

Ter Beek, O., Pavlenko, D., Suck, M., Helfrich, S., Bolhuis-Versteeg, L., Snisarenko, D., Causserand, C., Bacchin, P., Aimar, P., van Oerle, R., Wetzels, R., Verhezen, P., Henskens, Y. & Stamatialis, D. New membranes based on polyethersulfone - SlipSkin (TM) polymer blends with low fouling and high blood compatibility. Sep Purif Technol 2019; 225: 60-73. 

Heubel-Moenen FCJI, Henskens YMC, Verhezen PWM, Wetzels RJH, Schouten HC, Beckers EAM. Fibrinolysis in patients with chemotherapy-induced thrombocytopenia and the effect of platelet transfusion. J Thromb Haemost. 2019 Jul;17(7):1073-1084.

Damen SAJ, Vroemen WHM, Brouwer MA, Mezger STP, Suryapranata H, van Royen N, Bekers O, Meex SJR, Wodzig WKWH, Verheugt FWA, de Boer D, Cramer GE, Mingels AMA. Multi-Site Coronary Vein Sampling Study on Cardiac Troponin T Degradation in Non-ST-Segment-Elevation Myocardial Infarction: Toward a More Specific Cardiac Troponin T Assay. J Am Heart Assoc. 2019 Jul 16;8(14):e012602.

Holwerda AM, Paulussen KJM, Overkamp M, Goessens JPB, Kramer IF, Wodzig WKWH, Verdijk LB, van Loon LJC. Dose-Dependent Increases in Whole-Body Net Protein Balance and Dietary Protein-Derived Amino Acid Incorporation into Myofibrillar Protein During Recovery from Resistance Exercise in Older Men. J Nutr. 2019. 149(2):221-230.

Luijten J, van Greevenbroek MMJ, Schaper NC, Meex SJR, van der Steen C, Meijer LJ, de Boer D, de Graaf J, Stehouwer CDA, Brouwers MCGJ. Incidence of cardiovascular disease in familial combined hyperlipidemia: A 15-year follow-up study. Atherosclerosis. 2019 Jan;280:1-6.

Wijnen P, Drent M, Bekers O, Verschakelen J, Bast A. VKORC1 and CYP2C9 Polymorphisms: A Case Report in a Dutch Family with Pulmonary Fibrosis. Int J Mol Sci. 2019 Mar 7; 20 (5), 1160.

Jooss NJ, De Simone I, Provenzale I, Fernández DI, Brouns SLN, Farndale RW, Henskens YMC, Kuijpers MJE, Ten Cate H, van der Meijden PEJ, Cavill R, Heemskerk JWM. Role of Platelet Glycoprotein VI and Tyrosine Kinase Syk in Thrombus Formation on Collagen-Like Surfaces. Int J Mol Sci. 2019 Jun 7;20(11): 2788.

Holwerda AM, Paulussen KJM, Overkamp M, Goessens JPB, Kramer IF, Wodzig WKWH, Verdijk LB, de Groot LCPGM, van Loon LJC. Leucine co-ingestion augments the muscle protein synthetic response to the ingestion of 15 g protein following resistance exercise in older men. Am J Physiol Endocrinol Metab. 2019; 317 (3), E473-E482.

Posthuma, J. J., Posma, J. J. N., van Oerle, R., Leenders, P., van Gorp, R. H., Jaminon, A. M. G., Mackman, N., Heitmeier, S., Schurgers, L. J., ten Cate, H. & Spronk, H. M. H. Targetting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice. Scientific Reports. 2019; (9) 3909.

Mezger STP, Mingels AMA, Bekers O, Cillero-Pastor B, Heeren RMA. Trends in mass spectrometry imaging for cardiovascular diseases. Anal Bioanal Chem. 2019 Jul;411(17):3709-3720.

Vries MJA, Macrae F, Nelemans PJ, Kuiper GJAJM, Wetzels RJH, Bowman P, Verhezen PWM, Ten Cate H, Ariëns RAS, Henskens YMC. Assessment and determinants of whole blood and plasma fibrinolysis in patients with mild bleeding symptoms. Thromb Res. 2019 Feb;174:88-94. 

Posthuma, J. J., Posma, J. J. N., Schep, G., Bender, M. M. H., van Oerle, R., van der Wal, A. C., Ten Cate, H. & Spronk, H. M. H. Protease-activated receptors are potential regulators in the development of arterial endofibrosis in high-performance athletes. Journal of Vascular Surgery. 2019; 69 (4): 1243-1250.

Moenen FCJI, Vries MJA, Nelemans PJ, van Rooy KJM, Vranken JRRA, Verhezen PWM, Wetzels RJH, Ten Cate H, Schouten HC, Beckers EAM, Henskens YMC. Screening for platelet function disorders with Multiplate and platelet function analyzer. Platelets. 2019;30(1):81-87. 

Rolf L, Smolders J, van den Ouweland J, Hupperets, R, Damoiseaux J. Correlation of Different Cellular Assays to Analyze T Cell-Related Cytokine Profiles in Vitamin D 3-supplemented Patients With Multiple Sclerosis. Mol Immunol. 2019; 105: 198-204.

Gulpen AJW, Ten Cate H, Henskens YMC, van Oerle R, Wetzels R, Schalla S, Crijns HJ, Ten Cate-Hoek AJ. The daily practice of direct oral anticoagulant use in patients with atrial fibrillation; an observational cohort study. PLoS One. 2019 Jun 6;14(6):e0217302. 

Horstman AMH, Backx EMP, Smeets JSJ, Marzuca-Nassr GN, van Kranenburg J, Boer de D, Dolmans J, Snijders T, Verdijk LB, de Groot LCPGM, van Loon LJC. Nandrolone decanoate administration does not attenuate muscle atrophy during a short period of disuse. PLoS One. 2019 Jan 28;14(1): 1-15: e0210823. 

Hendrix MLE, Bons JAP, Alers NO, Severens-Rijvers CAH, Spaanderman MEA, Al-Nasiry S. Maternal vascular malformation in the placenta is an indicator for fetal growth restriction irrespective of neonatal birthweight. Placenta. 2019 Nov;87:8-15. 

Jessurun NT, Drent M, van Puijenbroek EP, Bekers O, Wijnen PA, Bast A. Drug-induced interstitial lung disease: role of pharmacogenetics in predicting cytotoxic mechanisms and risks of side effects. Curr Opin Pulm Med. 2019 25 (5), 468-477.

TeMpOH-1 study Grp & Scheepers, L., Henskens Y. et al. Clinical characteristics of women captured by extending the definition of severe postpartum haemorrhage with 'refractoriness to treatment': a cohort study 17 BMC Pregnancy and Childbirth. 2019; 19 (19): 19-36. 

Proesmans, V. L. J., Drent, M., Elfferich, M. D. P., Wijnen, P. A. H. M., Jessurun, N. T. & Bast, A. Self-reported Gastrointestinal Side Effects of Antifibrotic Drugs in Dutch Idiopathic Pulmonary Fibrosis patients Lung. 2019; 197 (5): 551-558. 

Hendrix MLE, Bons JAP, Snellings RRG, Bekers O, van Kuijk SMJ, Spaanderman MEA, Al-Nasiry S. Can Fetal Growth Velocity and First Trimester Maternal Biomarkers Improve the Prediction of Small-for-Gestational Age and Adverse Neonatal Outcome? Fetal Diagn Ther. 2019 46, 4, p. 274-284.

TeMpOH-Study Grp, Henriquez, D. D. C. A., Bloemenkamp, K. W. M., Loeff, R. M., Zwart, J. J., van Roosmalen, J. J. M., Zwaginga, J. J., van der Bom, J. G., Adriaanse, H. J., van den Akker, E. S. A., Baas, M. I., Bank, C. M. C., van Beek, E., de Boer, B. A., de Boer, K., van der Borden, D. M. R., Bremer, H. A., Brons, J. T. J., Burggraaff, J. M., Ceelie, H. & 31 others, Chon, H., Cikot, J. L. M., Delemarre, F. M. C., Diris, J. H. C., Doesburg-van Kleffens, M., van Dooren, I. M. A., van Duijnhoven, J. L. P., van Dunne, F. M., Duvekot, J. J., Engbers, P., Hulst, M. J. W. V. E., Feitsma, H., Fouraux, M. A., Franssen, M. T. M., Frasa, M. A. M., van Gammeren, A. J., van Gemund, N., van der Graaf, F., de Groot, C. J. M., Hackeng, C. M., van der Ham, D. P., Hanssen, M. J. C. P., Hasaart, T. H. M., Hendriks, H. A., Henskens, Y. M. C., Peters, R. H. M., Pouwels, J. G. J., Verhagen, T. E. M., Visser, H., de Vries, M. J. & de Wit, A. C. Fluid resuscitation during persistent postpartum haemorrhage and maternal outcome: A nationwide cohort study. EJOG 2019; 235: 49-56.

Kuiper GJAJM, van Egmond LT, Henskens YMC, Roekaerts PM, Maessen JG, Ten Cate H, Buhre WF, Lancé MD. Shifts of Transfusion Demand in Cardiac Surgery After Implementation of Rotational Thromboelastometry-Guided Transfusion Protocols: Analysis of the HEROES-CS (HEmostasis Registry of patiEntS in Cardiac Surgery) Observational, Prospective Open Cohort Database. J Cardiothorac Vasc Anesth. 2019 Feb;33(2):307-317. 

Krekels JPM, Verhezen PWM, Henskens YMC. Platelet Aggregation in Healthy Participants is Not Affected by Smoking, Drinking Coffee, Consuming a High-Fat Meal, or Performing Physical Exercise. Clin Appl Thromb Hemost. 2019 ;25: 1-9. 

Hendrix MLE, Palm KCM, Van Kuijk SMJ, Bekers O, Spaanderman MEA, Bons JAP, Al-Nasiry S. Longitudinal changes in placental biomarkers in women with early versus late placental dysfunction. Hypertens Pregnancy. 2019 Nov;38(4):268-277.

Cheung CY, Chan KM, Wong YT, Chak WL, Bekers O, van Hooff JP. Impact of CYP3A5 Genetic Polymorphism on Intrapatient Variability of Tacrolimus Exposure in Chinese Kidney Transplant Recipients.Transplant Proc. 2019 51, 6, p. 1754-1757 4 p. 

Voortman, M., De Vries, J., Hendriks, C. M. R., Elfferich, M. D. P., Wijnen, P. A. H. M. & Drent, M. Every congnitive failure in patients suffering from neurosarcoidosis. Sarcoidosis Vasc Diffus Lung Dis. 2019; 36: 2-10.

Vanderlocht J, van Beers JJBC, Limburg PC, Damoiseaux J, Roozendaal C. Antigen-Specific Detection of Autoantibodies Against Myeloperoxidase (MPO) and Proteinase 3 (PR3). Methods Mol Biol. 2019;1901:153-176. 

van Beers JJBC, Vanderlocht J, Roozendaal C, Damoiseaux J. Detection of Anti-neutrophil Cytoplasmic Antibodies (ANCA) by Indirect Immunofluorescence. Methods Mol Biol. 2019;1901:47-62. 

Benedikter, B. J., Bouwman, F. G., Heinzmann, A. C. A., Vajen, T., Mariman, E. C., Wouters, E. F. M., Savelkoul, P. H. M., Koenen, R. R., Rohde, G. G. U., van Oerle, R., Spronk, H. M. & Stassen, F. R. M. Proteomic analysis reveals procoagulant properties of cigarette smoke-induced extracellular vesicles. Journal of Extracellular Vesicles . 2019; 8 (1) 1585163. IF Research output: Contribution to journal › Article › Academic › peer-review.

Kremers, B. M. M., Birocchi, S., van Oerle, R., Zeerleder, S., Spronk, H. M. H., Mees, B. M. E., Luken, B. M., ten Cate, H. & ten Cate-Hoek, A. J. Searching for a Common Thrombo-Inflammatory Basis in Patients With Deep Vein Thrombosis or Peripheral Artery Disease Frontiers in cardiovascular medicine. 2019; 6: 1-11, Research output: Contribution to journal › Article › Academic › peer-review.

Peeters FECM, Kietselaer BLJH, Hilderink J, van der Linden N, Niens M, Crijns HJGM, Meex SJR. Biological variation of cardiac markers in patients with aortic valve stenosis. Open Heart. 2019 May 8;6(1):e001040.

Vroemen WHM, Mezger STP, Masotti S, Clerico A, Bekers O, de Boer D, Mingels A. Cardiac Troponin T: Only Small Molecules in Recreational Runners After Marathon Completion. J Appl Lab Med. 2019 Mar;3(5):909-911. 

Hwang P, Mingels A, Kavsak PA. High-sensitivity cardiac troponin testing during and after ACS: Complexed or not? Clin Biochem. 2019 Nov;73:32-34. 

Damoiseaux, J. Response to: 'Revised 2017 international consensus on ANCA testing in small vessel vasculitis: support from an external quality assessment' by Broeders et al 2019, In: Annals of the Rheumatic Diseases. 2019;78 (10): E114. Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review.

Meroni P, Chan E, Damoiseaux J, Coelho Andrade E, Bossuyt X, Conrad K, Mariette X, Sheldon J, Rönnelid, J Fritzler M, members of the committees. Unending Story of the Indirect Immunofluorescence Assay on HEp-2 Cells: Old Problems and New Solutions? Ann Rheum Dis 2019; 78 (6), e46.

Smolders J, Damoiseaux J, Hupperets R, Hypercalcaemia Rather Than High Dose Vitamin D3 Supplements Could Exacerbate Multiple Sclerosis. Brain. 2019 Dec 1: 142 (12), e71.

Damoiseaux, J.G.M.C., B. Meek, and C. Roozendaal (2019). De nieuwe internationale consensus met betrekking tot de ANCA-laboratorium-diagnostiek bij ANCA-geassocieerde vasculitis. Ned. Tijdschr. Allergie, Astma, Klin. Immunol. 19:103-110.

Damoiseaux, J.G.M.C. (2019). Consensus on ANA patterns (ICAP): from clinical association towards clinical relevance of HEp-2 indirect immunofluorescence patterns. In: “Precision medicine – role of autoantibodies in the prediction and care of autoimmune diseases” Conrad et al Eds. Volume 12: 384-390.

Damoiseaux, J.G.M.C., J. van Beers, and P. van Paassen (2019). Autoantibodies in disease criteria for systemic autoimmune diseases: developments in the last decade. In: “Mosaic of autoimmunity; the novel factors of autoimmune diseases” Perricone and Shoenfeld, Eds. (London: Academic Press), 81-89.